Crohn's Disease - Demonstration Project

Crohn's Disease phenotype algorithm for the DNA DataBank Demonstration Project.  Case records are required to have more than 2 occurrences of ICD 9 codes and medications.  Control records are required to not have ICD 9 codes or keyword mention of crohn* or Regional enteritis and excludes additional phenotypes as defined by ICD 9 codes and keywords.

Data source summary:

 

Diagnostic Codes?

Text Keywords?

Narrative Notes to search

Other rules

Cases

Yes

Disease and medication

H&P, Discharge summary, all notes

Pathology reports

Requires manual curation if dual diagnosis of Crohn’s and UC

Possible/

Probable

Yes

Disease only

H&P, Discharge summary, all notes

Pathology reports

Requires manual curation of all records

Controls

Yes

(Absence of codes)

Absence of keywords

All text

 

Excluded from Analysis

Yes

Disease only

All text

 

 

Data Modalities and Methods Used: 
Author: 
Josh Denny and Melissa Basford
Status: 
Groups audience: 
Institution: 
Date Created: 
Tuesday, March 20, 2012
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PubMed References

20362271