Phenotype: 
ACE Inhibitor (ACE-I) induced cough
Algorithm Type: 
Case, Control
Institution: 
Northwestern University The Feinberg School of Medicine
Implementation Details: 

When searching outside of the allergy list, we encountered too many false positives (many uncertain, speculative diagnoses). We restricted our search to notes that contained the word "allergies", and took  the following 200 characters. Within this 200 character window, we executed the following matches:

  • <ACEi-allergy> := <mention>.{0,20}<mention>
  • <mention> := <ACEi> | <cough>
  • <ACEi> := ACEI | ACE | (ACE Inhibitor) | (... list of drug names ...)
  • <cough> := cough | caugh

This strategy yielded 46 cases, all of which were judged to have an ACEi induced cough.

 

True Positive: 
46.00
False Positive: 
0.00
True Positive: 
43.00
False Positive: 
1.00
Case Positive Predictive Value: 
1.00
Control Positive Predictive Value: 
0.98