These are the algorithms for the PRIMED Harmonized systolic and diastolic blood pressures (SBP and DBP). The overall procedure of gathering single BP values per individual consists of:
This is the PRIMED Consortium algorithm to obtain a single Hba1c value per individual to use in analyses. Here is the overall procedures:
Objective
We leveraged existing data from a single electronic health care system in the southeastern United States to demonstrate the feasibility of measuring quality indicators for the hospital-based care of opioid-exposed newborns using existing data infrastructure. Additionally, we identified other key variables related to the care of opioid-exposed maternal-infant dyads.
Patients and Methods
We are using the prostate cancer definition used by the eMERGE program, with a slight modification to the control definition (prostate_cancer_status_emerge_mod_1). You can review the eMERGE documentation for reference, but please follow this document for implementation.
Modifications:
Combine “Control A” and “Control B” groups from the provided schematic figure into a single control group for analysis
Controls should be filtered based on age >= the minimum age of identified cases to the age distributions of cases and controls are comparable within each study
Systemic Lupus Erythematosus (SLE) is a chronic, systemic autoimmune disease that can affect many parts of the body including skin, lungs, brain, heart, kidneys, joints, and blood vessels. SLE presentation can vary significantly between patients. Because of this, it can be challenging to identify a patient as having SLE. Between 300,000 and 2,000,000 people in the US are estimated to have SLE. Determination of an exact number of people affected is challenging as the disease is difficult to identify given the diverse presentations and the length of time it may take for symptoms to appear.
There are two case algorithms provided for T2D. The first (t2d_dprism_ehr_plus_1) is the preferred case algorithm and includes self-reported T2D information collected from survey. The second (t2d_dprism_ehr_1) is an alternative case algorithm that does NOT include self-reported T2D information collected from survey.
We request harmonization based on the preferred algorithm, but if self-reported T2D survey information is not available, the alternative algorithm is acceptable.
These are the PRIMED harmonization instructions for white blood cell count (WBC).
To ascertain a single white blood cell count value per individual, adhere to the instructions as follows: