Pain is a personal, multidimensional experience in which genetic biomarkers has a main role in determining pain sensitivity, perception and tolerance. Pain is a major concern for surgical patients and post-operative pain management still present a major challenge both in inpatient or outpatient settings. Apart from genetic factors, there are many other variables that may affect pain perception for example, pretreated patients may require less post-surgical medications, and they may recover more quickly. Although there are no gold standard, numeric rating scale (NRS 0–10) are regularly used in postoperative pain treatment. The estimated tolerable postoperative pain before operation is median of NRS 4.0 (0–10). Patients who would need more analgesics reported significantly higher average pain since surgery median NRS 5.0 compared with those without this request NRS 3.0 (1).
Post-event Pain algorithm
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Thursday, September 1, 2016
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CCHMC. Post-event Pain algorithm. PheKB; 2016 Available from: https://phekb.org/phenotype/592